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CliP is an algorithm for clonal structure identification through penalizing pairwise differences by Wenyi Wang Lab at MD Anderson Cancer Center in Houston.

Usage

to_clip(
  cd,
  out_dir = NULL,
  snvs_name = default_SNVs(cd),
  cnvs_name = default_CNVs(cd),
  purity_column = "purity",
  keep_chromosomes = str_c("chr", 1:22)
)

Arguments

cd

cevodata object

out_dir

Directory where to save files. List of items is returned if out_dir is NULL

snvs_name

name of the snvs to use

cnvs_name

name of the cnvs to use

purity_column

name of the metadata column with the purity estimates to be used

keep_chromosomes

list of non-sex chromosomes. CliP does not use sex chromosomes