cevomod v2.3.0 released!
Starting from this update, cevomod can fit the binomial components of the model using the CliP algorithm introduced in Jiang et al., CliP: subclonal architecture reconstruction of cancer cells in DNA sequencing data using a penalized likelihood model, bioRxiv (2021).
Running CliP does not require installing anything but Apptainer (I wanted to implement methods for running external tools via containers for a long time). The CliP container image can be built with build_clip_container()
and CliP can be selected with method = "CliP
argument of fit_subclones()
function.
Check out the cevomod page and Model Fitting vignette for more details on usage of CliP in cevomod.